Proteomics core

The Proteomics Core Facility provides protein characterization by mass spectrometry. This includes identification of unknown proteins, quantitative comparison of proteins in biological samples, and mapping of post-translational protein modifications.

Instrumentation associated with the Proteomics Core includes state-of-the-art Orbitrap Fusion (Thermo) and LTQ Orbitrap Velos (Thermo) mass spectrometers. The core also maintains an on-site Mascot Server (Matrix Science) as well as MaxQuant (Max Planck Institute) and Scaffold Q+S, PTM and perSPECtives (Proteome Software) licenses for data analysis.

Get more information about submitting samples. If you have any questions, contact Sam Mackintosh.

 

IDeA National Resource for Proteomics

The IDeA National Resource for Proteomics is a partnership between the Arkansas INBRE (IDeA Network of Biomedical Research Excellence) and the Oklahoma INBRE. This partnership unites the cutting-edge, discovery phase proteomic capabilities at the University of Arkansas for Medical Sciences (UAMS) Proteomics Facility with the state-of-the-art, targeted validation proteomics at the Oklahoma Medical Research Foundation (OMRF) Multiplexing Protein Quantification Core to create a national proteomics resource for the IDeA (Institutional Development Award) Program.

The UAMS Proteomics Facility has mass spectrometers specific for discovery phase proteomics, while the OMRF Multiplexing Protein Quantification Core is equipped with instrumentation for targeted validation proteomics. Both cores are operated with a fee-for-service model. Consultation with our individual core directors is strongly encouraged prior to submitting a sample for analysis. 

 

Center for Translational Pediatric Research

The Center for Translational Pediatric Research (CTPR) seeks to investigate how pediatric diseases develop from a systems biology and mechanistic approach, with the ultimate goal of identifying the intersections of disease and development, which will produce targets for therapeutic intervention and the development of new treatments. Systems biology is an integrated approach examining all events within cells, tissues, and organisms that lead to a particular outcome. By applying a systems biology approach to the study of pediatric diseases, the CTPR hopes to expand existing knowledge of pediatric disease development and contribute to new therapeutic targets. The long term goal of the CTPR is to build an innovative, multi-disciplinary pediatric research center that utilizes cutting-edge systems biology technologies and state-of-the-art translational research to study pediatric diseases.

 

Equipment Repair

Instrumentation Service is provided for basic science departments in the College of Medicine departments